Tissue-engineered skeletal muscle organoids for reversible gene therapy
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Tissue-engineered skeletal muscle organoids for reversible gene therapy brief report

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Published by National Aeronautics and Space Administration, National Technical Information Service, distributor in [Washington, DC, Springfield, Va .
Written in English


  • Musculoskeletal system.,
  • Pituitary hormones.,
  • Muscles.,
  • Cells (Biology),
  • Genes.,
  • Therapy.

Book details:

Edition Notes

Other titlesTissue engineered skeletal muscle organoids for reversible gene therapy
StatementHerman Vandenburgh ... [et al.].
Series[NASA contractor report] -- NASA/CR-96-207803, NASA contractor report -- NASA CR-207803.
ContributionsVandenburgh, Herman., United States. National Aeronautics and Space Administration.
The Physical Object
Pagination1 v.
ID Numbers
Open LibraryOL17131769M

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Chromiak J.A., Shansky J., Perrone C., Vandenburgh H.H. Bioreactor perfusion system for the long-term maintenance of tissue-engineered skeletal muscle agabbayetassocies.com: Robert G. Dennis. Get this from a library! Tissue-engineered skeletal muscle organoids for reversible gene therapy: brief report. [Herman H Vandenburgh; United States. National Aeronautics and Space Administration.;]. Skeletal muscle transplantation strategies for muscle repair or gene therapy involve either the injection of proliferating myoblasts followed by fusion with host myofibers or implantation of ex. A multilevel finite element approach is applied to predict local cell deformations in engineered tissue constructs. Cell deformations are predicted from detailed nonlinear FE analysis of the microstructure, consisting of an arrangement of cells embedded in matrix agabbayetassocies.com by:

Skeletal muscle tissue engineering involves the culture of muscle precursor cells (MPCs) on or within a suitable scaffold material. There are multiple reasons why the creation of biomimetic skeletal muscle constructs is of interest: l. To study the basic physiology and biochemistry of skeletal agabbayetassocies.com by: 3. Three-dimensional skeletal muscle organ-like structures (organoids) formed in tissue culture by fusion of proliferating myoblasts into parallel networks of long, unbranched myofibers provide an in. Traditional two-dimensional culture systems suffer from inherent limitations that motivate the need to develop three-dimensional (3D) platforms for stem cell culture to provide greater insights into in vivo function and enable advanced applications, such as tissue-engineered constructs, biomanufacturing approaches, and platforms for drug discovery and toxicity agabbayetassocies.com by: 1. Gene therapy of salivary diseases -- Collection, storage, and processing of saliva samples for downstream molecular applications -- Proteomic analysis of saliva: 2D gel electrophoresis, LC-MS/MS, and Western blotting -- Transcriptomic analyses of saliva -- The oral microbiota: General overview, taxonomy, and nucleic acid techniques.

While each iPS cell therapy group is considered in detail below, Cellular Dynamics International (CDI) is featured first, because it dominates the iPSC industry. CDI also recently split into two business units, a Life Science Unit and a Therapeutics Unit, demonstrating a commercial strategy for . Interrogating functional and molecular properties of PAX7+ putative skeletal muscle stem/progenitor cells derived from human iPSCs of healthy donors and Duchenne muscular dystrophy patients Human tissue-engineered blood vessels using induced pluripotent stem cells Cancer Cell and Gene Therapy Program (Project). Thus, the challenge of industrial bioseparation can be summed up as: The need to perform an economically sound, high-resolution separation on a large scale, while maintaining “physiological” conditions throughout. Synthetic Polymers for Biotechnology and Medicine, edited by Ruth Freitag. © agabbayetassocies.com Cardiac muscle (heart muscle) is an involuntary, striated muscle that is found in the walls and histological foundation of the heart, specifically the myocardium. Cardiac muscle is one of three major types of muscle, the others being skeletal and smooth muscle. These .